An Electronic Investigator Site File (eISF) Built for Compliance
Audit-ready, collaborative, and fully paperless
An Electronic Investigator Site File (eISF) Built for Compliance
Audit-ready, collaborative, and fully paperless
An Electronic Investigator Site File (eISF) Built for Compliance
Audit-ready, collaborative, and fully paperless
Organize Your Study Documents in Digital Binders
Ditch the filing cabinets. SiteCentric eISF lets you store and manage all site and study-specific documents in structured digital binders. From protocols to licenses to logs, everything is in one secure, searchable place—ready for sponsors, CRAs, and auditors.
Organize Your Study Documents in Digital Binders
Ditch the filing cabinets. SiteCentric eISF lets you store and manage all site and study-specific documents in structured digital binders. From protocols to licenses to logs, everything is in one secure, searchable place—ready for sponsors, CRAs, and auditors.
Organize Your Study Documents in Digital Binders
Ditch the filing cabinets. SiteCentric eISF lets you store and manage all site and study-specific documents in structured digital binders. From protocols to licenses to logs, everything is in one secure, searchable place—ready for sponsors, CRAs, and auditors.
Bulk Upload with Drag-and-Drop & Email Forwarding
Upload files with ease using drag-and-drop or simply forward emails with attachments to your site’s eISF inbox. Documents are automatically filed and can be routed to multiple studies—saving time and reducing manual entry.
Bulk Upload with Drag-and-Drop & Email Forwarding
Upload files with ease using drag-and-drop or simply forward emails with attachments to your site’s eISF inbox. Documents are automatically filed and can be routed to multiple studies—saving time and reducing manual entry.
Bulk Upload with Drag-and-Drop & Email Forwarding
Upload files with ease using drag-and-drop or simply forward emails with attachments to your site’s eISF inbox. Documents are automatically filed and can be routed to multiple studies—saving time and reducing manual entry.
Centralized Master File Management
Manage non-study documents like CVs, licenses, and training certifications in a single Site Master File. When an update is made, SiteCentric automatically syncs it across all active study binders—so you’re always working with the latest version.
Centralized Master File Management
Manage non-study documents like CVs, licenses, and training certifications in a single Site Master File. When an update is made, SiteCentric automatically syncs it across all active study binders—so you’re always working with the latest version.
Centralized Master File Management
Manage non-study documents like CVs, licenses, and training certifications in a single Site Master File. When an update is made, SiteCentric automatically syncs it across all active study binders—so you’re always working with the latest version.
Enable Remote Monitoring in One Click
Provide CRAs and auditors with secure, permission-based access to eISF binders. They can monitor changes, view document status, and conduct remote reviews—all without the hassle of separate portals or manual uploads.
Enable Remote Monitoring in One Click
Provide CRAs and auditors with secure, permission-based access to eISF binders. They can monitor changes, view document status, and conduct remote reviews—all without the hassle of separate portals or manual uploads.
Enable Remote Monitoring in One Click
Provide CRAs and auditors with secure, permission-based access to eISF binders. They can monitor changes, view document status, and conduct remote reviews—all without the hassle of separate portals or manual uploads.
Digitally Sign and Route Documents for Approval
Streamline your document approval workflows with built-in eSignatures. Staff can sign electronically in a defined order, and SiteCentric tracks every action—creating a complete audit trail.
Digitally Sign and Route Documents for Approval
Streamline your document approval workflows with built-in eSignatures. Staff can sign electronically in a defined order, and SiteCentric tracks every action—creating a complete audit trail.
Digitally Sign and Route Documents for Approval
Streamline your document approval workflows with built-in eSignatures. Staff can sign electronically in a defined order, and SiteCentric tracks every action—creating a complete audit trail.
Never Miss a Document Expiration Again
Get proactive notifications when documents are approaching expiration. Stay ahead of GCP compliance with auto-alerts for CVs, licenses, training records, and other time-sensitive documentation.
Never Miss a Document Expiration Again
Get proactive notifications when documents are approaching expiration. Stay ahead of GCP compliance with auto-alerts for CVs, licenses, training records, and other time-sensitive documentation.
Never Miss a Document Expiration Again
Get proactive notifications when documents are approaching expiration. Stay ahead of GCP compliance with auto-alerts for CVs, licenses, training records, and other time-sensitive documentation.
Track Training and Staff Credentialing
Securely store and link study-specific training records to your binders. View training status by staff or study, identify gaps, and produce audit-ready reports in seconds.
Track Training and Staff Credentialing
Securely store and link study-specific training records to your binders. View training status by staff or study, identify gaps, and produce audit-ready reports in seconds.
Track Training and Staff Credentialing
Securely store and link study-specific training records to your binders. View training status by staff or study, identify gaps, and produce audit-ready reports in seconds.
Digitally Track Your Paper Archives
Still have some paper? No problem. SiteCentric enables barcode-based tracking of physical study documents and archive boxes, so you always know where critical records are stored—and when they’re eligible for destruction.
Digitally Track Your Paper Archives
Still have some paper? No problem. SiteCentric enables barcode-based tracking of physical study documents and archive boxes, so you always know where critical records are stored—and when they’re eligible for destruction.
Digitally Track Your Paper Archives
Still have some paper? No problem. SiteCentric enables barcode-based tracking of physical study documents and archive boxes, so you always know where critical records are stored—and when they’re eligible for destruction.
Built-In Blockchain Integrity and Part 11 Compliance
Every document uploaded to SiteCentric’s eISF is cryptographically fingerprinted using blockchain technology. This ensures authenticity, prevents tampering, and supports 21 CFR Part 11 compliance right out of the box.
Built-In Blockchain Integrity and Part 11 Compliance
Every document uploaded to SiteCentric’s eISF is cryptographically fingerprinted using blockchain technology. This ensures authenticity, prevents tampering, and supports 21 CFR Part 11 compliance right out of the box.
Built-In Blockchain Integrity and Part 11 Compliance
Every document uploaded to SiteCentric’s eISF is cryptographically fingerprinted using blockchain technology. This ensures authenticity, prevents tampering, and supports 21 CFR Part 11 compliance right out of the box.
I can say, having worked at the site and CRO levels, any site serious about the quality and efficiency of their data, along with the importance of having a cohesive work environment, would take a long hard look at this platform.
Joan Cutillo, CRA II Premier Research
I can say, having worked at the site and CRO levels, any site serious about the quality and efficiency of their data, along with the importance of having a cohesive work environment, would take a long hard look at this platform.
Joan Cutillo, CRA II Premier Research
I can say, having worked at the site and CRO levels, any site serious about the quality and efficiency of their data, along with the importance of having a cohesive work environment, would take a long hard look at this platform.
Joan Cutillo, CRA II Premier Research
FAQ's
Frequently asked questions on the eISF Module
FAQ's
Frequently asked questions on the eISF Module
FAQ's
Frequently asked questions on the eISF Module
What is an eISF and why does it matter?
An electronic Investigator Site File (eISF) replaces traditional paper binders with a secure digital system to manage regulatory and study-related documents. It helps sites stay organized, reduce errors, and be audit-ready at all times.
What is an eISF and why does it matter?
An electronic Investigator Site File (eISF) replaces traditional paper binders with a secure digital system to manage regulatory and study-related documents. It helps sites stay organized, reduce errors, and be audit-ready at all times.
What is an eISF and why does it matter?
An electronic Investigator Site File (eISF) replaces traditional paper binders with a secure digital system to manage regulatory and study-related documents. It helps sites stay organized, reduce errors, and be audit-ready at all times.
Can we use our existing documents and folders in SiteCentric?
Yes! You can upload files or forward them via email, then easily organize them with drag and drop; you can even use your existing naming conventions. SiteCentric also supports structured study binders and master file templates to simplify setup.
Can we use our existing documents and folders in SiteCentric?
Yes! You can upload files or forward them via email, then easily organize them with drag and drop; you can even use your existing naming conventions. SiteCentric also supports structured study binders and master file templates to simplify setup.
Can we use our existing documents and folders in SiteCentric?
Yes! You can upload files or forward them via email, then easily organize them with drag and drop; you can even use your existing naming conventions. SiteCentric also supports structured study binders and master file templates to simplify setup.
Is the SiteCentric eISF Part 11 compliant?
Absolutely. SiteCentric meets all 21 CFR Part 11 requirements, including secure access controls, eSignatures, audit trails, and version tracking. Each document is also protected with a blockchain-based digital fingerprint to ensure its integrity.
Is the SiteCentric eISF Part 11 compliant?
Absolutely. SiteCentric meets all 21 CFR Part 11 requirements, including secure access controls, eSignatures, audit trails, and version tracking. Each document is also protected with a blockchain-based digital fingerprint to ensure its integrity.
Is the SiteCentric eISF Part 11 compliant?
Absolutely. SiteCentric meets all 21 CFR Part 11 requirements, including secure access controls, eSignatures, audit trails, and version tracking. Each document is also protected with a blockchain-based digital fingerprint to ensure its integrity.
How does remote monitoring work in SiteCentric?
CRAs and auditors are given secure, permission-based access to view eISF documents remotely. They can see what’s changed since their last review and download approved files—without needing additional logins or manual uploads from your team.
How does remote monitoring work in SiteCentric?
CRAs and auditors are given secure, permission-based access to view eISF documents remotely. They can see what’s changed since their last review and download approved files—without needing additional logins or manual uploads from your team.
How does remote monitoring work in SiteCentric?
CRAs and auditors are given secure, permission-based access to view eISF documents remotely. They can see what’s changed since their last review and download approved files—without needing additional logins or manual uploads from your team.
What happens when a document expires?
SiteCentric automatically notifies the appropriate staff when documents—like CVs, training logs, or licenses—are nearing expiration. When an updated document is uploaded, it is automatically synced across all linked study binders.
What happens when a document expires?
SiteCentric automatically notifies the appropriate staff when documents—like CVs, training logs, or licenses—are nearing expiration. When an updated document is uploaded, it is automatically synced across all linked study binders.
What happens when a document expires?
SiteCentric automatically notifies the appropriate staff when documents—like CVs, training logs, or licenses—are nearing expiration. When an updated document is uploaded, it is automatically synced across all linked study binders.
Can we track training and credentialing inside the eISF?
Yes. Staff training records are securely stored and linked to the appropriate study binders. You can generate reports by study, staff member, or training topic to demonstrate compliance during audits.
Can we track training and credentialing inside the eISF?
Yes. Staff training records are securely stored and linked to the appropriate study binders. You can generate reports by study, staff member, or training topic to demonstrate compliance during audits.
Can we track training and credentialing inside the eISF?
Yes. Staff training records are securely stored and linked to the appropriate study binders. You can generate reports by study, staff member, or training topic to demonstrate compliance during audits.
See how every module works together to elevate your site
See how every module works together to elevate your site
See how every module works together to elevate your site
All Rights Reserved © 2025 SiteCentric.
SiteCentric, SiteCentric CTMS, and SiteCentric Clinical Trial Management Software and affiliated logos are registered trademarks owned by Clinical Neuroscience Solutions, Inc. d/b/a SiteCentric.
All other trademarks, names, and logos referenced on the SiteCentric website are the property of their respective owners. Any use of third-party trademarks is for identification and informational purposes only and does not imply any affiliation, endorsement, or sponsorship by those third parties.
All Rights Reserved © 2025 SiteCentric.
SiteCentric, SiteCentric CTMS, and SiteCentric Clinical Trial Management Software and affiliated logos are registered trademarks owned by Clinical Neuroscience Solutions, Inc. d/b/a SiteCentric.
All other trademarks, names, and logos referenced on the SiteCentric website are the property of their respective owners. Any use of third-party trademarks is for identification and informational purposes only and does not imply any affiliation, endorsement, or sponsorship by those third parties.
All Rights Reserved © 2025 SiteCentric.
SiteCentric, SiteCentric CTMS, and SiteCentric Clinical Trial Management Software and affiliated logos are registered trademarks owned by Clinical Neuroscience Solutions, Inc. d/b/a SiteCentric.
All other trademarks, names, and logos referenced on the SiteCentric website are the property of their respective owners. Any use of third-party trademarks is for identification and informational purposes only and does not imply any affiliation, endorsement, or sponsorship by those third parties.